{"id":114,"date":"2026-09-25T15:26:08","date_gmt":"2026-09-25T15:26:08","guid":{"rendered":"https:\/\/sachastaliklari.org.tr\/?page_id=114"},"modified":"2026-09-27T20:18:39","modified_gmt":"2026-09-27T20:18:39","slug":"atopik-ve-kontakt-dermatit","status":"publish","type":"page","link":"https:\/\/sachastaliklari.org.tr\/?page_id=114","title":{"rendered":"Atopik ve Kontakt Dermatit"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"114\" class=\"elementor elementor-114\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1b16ebc e-flex e-con-boxed e-con e-parent\" data-id=\"1b16ebc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1851dac elementor-widget elementor-widget-html\" data-id=\"1851dac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<article class=\"medical-guide-page\">\r\n    <h1>Atopik Dermatit ve Kontakt Dermatit (Alerjik ve Tahri\u015f Edici Reaksiyonlar) \u2013 Tan\u0131 ve Tedavi Rehberi<\/h1>\r\n    <p class=\"author-meta\"><strong>Haz\u0131rlayan:<\/strong> Dr. Muhammet \u00d6zgehan | T\u00fcrkiye Sa\u00e7 ve Sa\u00e7 Deri Hastal\u0131klar\u0131 Derne\u011fi<\/p>\r\n    <p class=\"compilation-meta\"><em>Bu rehber, Dr. Muhammet \u00d6zgehan taraf\u0131ndan derlenmi\u015ftir.<\/em><\/p>\r\n\r\n    <!-- Ortam K\u00fct\u00fcphanesinden Eklenen Medikal \u0130ll\u00fcstrasyon -->\r\n    <div class=\"medical-illustration-container\" style=\"margin: 20px 0; text-align: center;\">\r\n        <img decoding=\"async\" src=\"https:\/\/sachastaliklari.org.tr\/wp-content\/uploads\/2026\/09\/sacli-deri-atopik-ve-kontakt-dermatit-dr-muhammet-ozgehan.png\" alt=\"Sa\u00e7l\u0131 Deri Atopik ve Kontakt Dermatit Klinik ve Medikal \u0130ll\u00fcstrasyonu\" style=\"max-width: 100%; height: auto; border-radius: 8px; box-shadow: 0 4px 12px rgba(0,0,0,0.1);\">\r\n    <\/div>\r\n\r\n    <section class=\"patient-info\">\r\n        <h2>\ud83d\udccc Hasta Bilgilendirme B\u00f6l\u00fcm\u00fc: Bu Durum Ne Anlama Geliyor?<\/h2>\r\n        <p>Sa\u00e7l\u0131 derimiz d\u0131\u015f etkenlere kar\u015f\u0131 olduk\u00e7a hassast\u0131r. Bu kategoride, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin a\u015f\u0131r\u0131 hassasiyetiyle ya da kimyasal maddelerin do\u011frudan temas\u0131yla olu\u015fan egzemalar incelenir:<\/p>\r\n        <ul>\r\n            <li><strong>Atopik Dermatit (Sa\u00e7 Derisi Tutulumu):<\/strong> Genellikle genetik olarak alerjik b\u00fcnyeye sahip (ast\u0131m, saman nezlesi \u00f6yk\u00fcs\u00fc olan) ki\u015filerde, \u00f6zellikle bebeklik\/\u00e7ocukluk \u00e7a\u011f\u0131nda veya eri\u015fkinlerde sa\u00e7l\u0131 deride ve ense k\u00f6k\u00fcnde \u015fiddetli ka\u015f\u0131nt\u0131, kuruluk ve pullanma ile kendini g\u00f6sterir.<\/li>\r\n            <li><strong>Alerjik Kontakt Dermatit:<\/strong> Sa\u00e7 boyalar\u0131 (\u00f6zellikle siyah boyalardaki PPD - parafenilendiamin maddesi), \u015fampuanlar, parf\u00fcmler veya sa\u00e7 bak\u0131m \u00fcr\u00fcnlerinin i\u00e7indeki baz\u0131 kimyasallara kar\u015f\u0131 cildin geli\u015ftirdi\u011fi alerjik reaksiyondur. Uygulamadan saatler veya g\u00fcnler sonra sa\u00e7l\u0131 deride, al\u0131n \u00e7izgisinde, kulak arkalar\u0131nda ve boyunda \u015fiddetli k\u0131zar\u0131kl\u0131k, \u00f6dem (\u015fi\u015flik) ve sulant\u0131l\u0131 yaralar olu\u015fturabilir.<\/li>\r\n            <li><strong>\u0130rritan Kontakt Dermatit:<\/strong> Alerji olmasa bile sa\u00e7 derisine \u00e7ok sert kimyasallar\u0131n, a\u011fart\u0131c\u0131lar\u0131n veya yanl\u0131\u015f uygulanan yo\u011fun sol\u00fcsyonlar\u0131n (\u00f6rn. yanl\u0131\u015f a\u00e7\u0131c\u0131lar) do\u011frudan deriyi yakmas\u0131 ve tahri\u015f etmesidir.<\/li>\r\n        <\/ul>\r\n    <\/section>\r\n\r\n    <section class=\"doctor-guide\">\r\n        <h2>\ud83e\ude7a Hekimler \u0130\u00e7in Klinik & Medikal K\u0131lavuz<\/h2>\r\n        <ul>\r\n            <li><strong>Etyoloji ve Patofizyoloji:<\/strong>\r\n                <ul>\r\n                    <li><em>Atopik Dermatit:<\/em> Cilt bariyer bozuklu\u011fu (filaggrin mutasyonlar\u0131) ve Tip 2 T-h\u00fccresi arac\u0131l\u0131 enflamatuar yan\u0131t.<\/li>\r\n                    <li><em>Kontakt Dermatit:<\/em> Tip IV gecikmi\u015f tip a\u015f\u0131r\u0131 duyarl\u0131l\u0131k reaksiyonu (alerjik) veya kimyasal ajanlar\u0131n stratum korneumu y\u0131kmas\u0131yla olu\u015fan toksik doku hasar\u0131 (irritan).<\/li>\r\n                <\/ul>\r\n            <\/li>\r\n            <li><strong>Tan\u0131 Kriterleri ve Klinik Bulgular:<\/strong> Sa\u00e7 s\u0131n\u0131rlar\u0131nda eritem, \u00f6dem, vezik\u00fcllenme (sulant\u0131), krutlanma ve kronik ka\u015f\u0131maya ba\u011fl\u0131 likenifikasyon (derinin kal\u0131nla\u015fmas\u0131). Sa\u00e7 boyas\u0131 alerjilerinde y\u00fcz\u00fc ve g\u00f6z kapaklar\u0131n\u0131 i\u00e7ine alan \u00f6demli reaksiyonlar.<\/li>\r\n            <li><strong>Dermoskopi (Trikoskopi) Bulgular\u0131:<\/strong> Akut d\u00f6nemde interfolik\u00fcler alanda sar\u0131ms\u0131 sulant\u0131 odaklar\u0131, eks\u00fcda krutlar\u0131, d\u00fczensiz vask\u00fcler yap\u0131lar ve ka\u015f\u0131maya ba\u011fl\u0131 travmatik ekskorasyon izleri.<\/li>\r\n            <li><strong>Histopatolojik Tan\u0131 (Punch Biyopsisi):<\/strong> \r\n                <ul>\r\n                    <li><em>Biyopsi Endikasyonu ve Tekni\u011fi:<\/em> Atipik egzemalarda veya di\u011fer skatrisyel\/non-skatrisyel alopesilerden ay\u0131rt etmekta zorlan\u0131lan diren\u00e7li vakalarda <strong>4 mm punch biyopsi<\/strong> al\u0131n\u0131r. \u0130nceleme <strong>vertikal kesitler<\/strong> ile yap\u0131l\u0131r.<\/li>\r\n                    <li><em>Patolojik Bulgular:<\/em> Epidermiste belirgin spongiyoz (h\u00fccreler aras\u0131 \u00f6dem ve vezik\u00fcl olu\u015fumu), akantoz, parakeratoz ve y\u00fczeysel perivask\u00fcler lenfositik ile eozinofilik (alerjik olgularda) infiltrat.<\/li>\r\n                <\/ul>\r\n            <\/li>\r\n            <li><strong>G\u00fcncel Tedavi Protokolleri:<\/strong> \r\n                <ul>\r\n                    <li><em>Temas\u0131n Kesilmesi ve Bariyer Onar\u0131m\u0131:<\/em> Alerjen oldu\u011fundan \u015f\u00fcphelenilen sa\u00e7 boyas\u0131, \u015fampuan ve kimyasal \u00fcr\u00fcnlerin derhal kesilmesi. Cilt bariyerini onar\u0131c\u0131 nemlendirici losyonlar.<\/li>\r\n                    <li><em>Antiinflamatuar Tedavi:<\/em> Akut sulant\u0131l\u0131 d\u00f6nemde k\u0131sa s\u00fcreli orta\/g\u00fc\u00e7l\u00fc potense sahip topikal kortikosteroid losyonlar veya kalsin\u00f6rin inhibit\u00f6rleri (takrolimus\/pimekrolimus).<\/li>\r\n                    <li><em>Sistemik Yakla\u015f\u0131m:<\/em> \u015eiddetli \u00f6dem ve alerjik reaksiyonlarda k\u0131sa k\u00fcr sistemik kortikosteroidler ve sedatif antihistaminikler. Alerjen tespiti i\u00e7in dermatoloji kliniklerinde Yama Testi (Patch Test) planlanmas\u0131. Ayr\u0131ca klinik ve cerrahi de\u011ferlendirmeler i\u00e7in <a href=\"https:\/\/www.muhammetozgehan.com.tr\" target=\"_blank\" rel=\"noopener\">uzmanl\u0131k ve tedavi yakla\u015f\u0131mlar\u0131<\/a> incelenebilir.<\/li>\r\n                <\/ul>\r\n            <\/li>\r\n        <\/ul>\r\n    <\/section>\r\n\r\n    <section class=\"scientific-references\" style=\"margin-top: 40px; padding-top: 20px; border-top: 1px solid #eaeaea;\">\r\n        <h3>Bilimsel Referanslar ve Daha Fazla Bilgi<\/h3>\r\n        <ul style=\"font-size: 0.95em; line-height: 1.6;\">\r\n            <li>Cuyler M, Twilley D, Lall N. Eczema: etiology, subtypes, therapeutic approaches and socioeconomic impact. <em>Front Allergy<\/em>. 2026 Jan 12;6:1675475. doi: 10.3389\/falgy.2025.1675475. PMID: 41602867; PMCID: PMC12833359. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41602867\/\" target=\"_blank\" rel=\"noopener\">PubMed Linki<\/a><\/li>\r\n            <li>Blicharz L, Michalczyk A, Maj M, Czuwara J, Olszewska M, Rudnicka L. Head and neck dermatitis: a variant of atopic dermatitis. <em>Ital J Dermatol Venerol<\/em>. 2025 Apr;160(2):123-144. doi: 10.23736\/S2784-8671.25.08001-6. PMID: 40248964. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40248964\/\" target=\"_blank\" rel=\"noopener\">PubMed Linki<\/a><\/li>\r\n            <li>Navarro-Trivi\u00f1o FJ, Salazar-Nievas M, Sanz-Cabanillas JL, Arjona-Aguilera C. Efficacy and safety of tralokinumab in the treatment of head and neck pattern atopic dermatitis: A multicentre study of 12 patients. <em>Australas J Dermatol<\/em>. 2024 May;65(3):260-265. doi: 10.1111\/ajd.14264. Epub 2024 Apr 8. PMID: 38587232. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38587232\/\" target=\"_blank\" rel=\"noopener\">PubMed Linki<\/a><\/li>\r\n        <\/ul>\r\n    <\/section>\r\n<\/article>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Atopik Dermatit ve Kontakt Dermatit (Alerjik ve Tahri\u015f Edici Reaksiyonlar) \u2013 Tan\u0131 ve Tedavi Rehberi Haz\u0131rlayan: Dr. Muhammet \u00d6zgehan | [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-114","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sachastaliklari.org.tr\/index.php?rest_route=\/wp\/v2\/pages\/114","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sachastaliklari.org.tr\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sachastaliklari.org.tr\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sachastaliklari.org.tr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sachastaliklari.org.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=114"}],"version-history":[{"count":7,"href":"https:\/\/sachastaliklari.org.tr\/index.php?rest_route=\/wp\/v2\/pages\/114\/revisions"}],"predecessor-version":[{"id":239,"href":"https:\/\/sachastaliklari.org.tr\/index.php?rest_route=\/wp\/v2\/pages\/114\/revisions\/239"}],"wp:attachment":[{"href":"https:\/\/sachastaliklari.org.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=114"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}